Vivanti, A, Vauloup-Fellous, C, Prevot, S, Zupan, V, Suffee, C, Do Cao, J, et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. Allotey, J, Stallings, E, Bonet, M, Yap, M, Chatterjee, S, Kew, T, et al. Reversing physician hesitancy to recommend COVID-19 vaccination for pregnant patients. Chervenak, FA, McCullough, LB, Grünebaum, A. Professionally responsible coronavirus disease 2019 vaccination counseling of obstetrical and gynecologic patients. Chervenak, FA, McCullough, LB, Bornstein, E, Johnson, A, Katz, A, McLeod-Sordjan, R, et al. John stuart mill and COVID-19 vaccinations in pregnancy today. The SARS-CoV-2 receptor ACE2 expression of maternal-fetal interface and fetal organs by single-cell transcriptome study. Li, M, Chen, L, Zhang, J, Xiong, C, Li, X. The immune system in pregnancy: a unique complexity. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection. WAPM (World Association of Perinatal Medicine) Working Group on COVID-19. Risk factors associated with adverse fetal outcomes in pregnancies affected by coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19. Di Mascio, D, Sen, C, Saccone, G, Galindo, A, Grünebaum, A, Yoshimatsu, J, et al. Alberca, R, Pereira, N, Oliveira, L, Gozzi-Silva, S, Sato, M. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Huang, C, Wang, Y, Li, X, Ren, L, Zhao, J, Hu, Y, et al. COVID-19 infection: the perspectives on immune responses. Shi, Y, Wang, Y, Shao, C, Huang, J, Gan, J, Huang, X, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. Wang, D, Hu, B, Hu, C, Zhu, F, Liu, X, Zhang, J, et al. Characteristics of SARS-CoV-2 and COVID-19. Is pregnancy a risk factor of COVID-19? Eur J Obstet Gynecol 2020 252:605–9. All healthcare providers should put more effort into education of pregnant women on risks of COVID-19, as well as on the benefits and safety of the vaccines.Īuthor contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.Ĭompeting interests: Authors state no conflict of interest.Įthical approval: Ethical approval was obtained from the University of Zagreb, School of Medicine, as well as from both of the institutions where the study was conducted.ġ. This study showed that the crucial reasons for refusing vaccination against COVID-19 among pregnant women in Croatia are the concerns about the vaccines’ effectiveness and safety. 21 (5%) women stated that vaccination against influenza and pertussis during pregnancy is necessary and 13 (62%) of them would get vaccinated against COVID-19 if offered. Only one out of 55 women who were not adherent to the current vaccination recommendations in Croatia would accept the COVID-19 vaccine during pregnancy if offered. The relationship exists between acceptance of vaccination in general and willingness to get other vaccines in pregnancy and readiness to be vaccinated against COVID-19 in pregnancy. The most important obstacle in having better acceptance of the vaccines is in the assumption that the vaccines are not safe for pregnant women (73%) or the fetus (75%), or that the vaccines are not effective (41%). Only 16% of women expressed their willingness to be vaccinated against COVID-19 if offered, despite that 71% of them believe that COVID-19 might be a serious illness in pregnant women. ResultsĪ total of 430 women participated in the study. During antenatal clinic visit pregnant women were approached and asked to fill out a predesigned questionnaire about their knowledge and attitudes towards COVID-19 vaccination. MethodsĪ cross-sectional study was performed in two teaching hospitals between May and October 2021 in Zagreb, Croatia. The aim of this study was to assess pregnant women’s knowledge and attitudes regarding maternal COVID-19 immunization during pregnancy.

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